Peter Kioso – who was recalled yesterday from his loan spell with Milton Keynes – starts in place of James Bree, who sits out this one with a tight hamstring sustained against Bournemouth, having played every minute of the Hatters' league and FA Cup matches this season.
Reece Burke and Allan Campbell are both fit and in the starting eleven after coming off during Saturday’s 3-2 win against AFC Bournemouth, whilst Cameron Jerome starts for the second league match in succession alongside Elijah Adebayo up-front.
Town: Shea; Kioso, Burke, Bradley (C), Naismith, Bell; Campbell, Mpanzu, Clark; Jerome, Adebayo.
Substitutes: Sluga, Potts, Berry, Mendes Gomes, Lansbury, Onyedinma, Osho.
Reading: Southwood, Holmes, Morrison (C), Rinomhota, Swift, Drinkwater, Dele Bashiru, Laurent, E. Bristow, Puscas, Ashcroft.
Substitutes: Holden, Joao, Camara, Clarke, Abrefa, Holzman
Referee: Tim Robinson