Rob Edwards’ side fell to a late defeat at Tottenham Hotspur on Saturday, just five miles away from Wednesday’s venue.
Mikel Arteta’s Arsenal have not lost a Premier League game in 2024 after Sunday’s goalless draw at title rivals Manchester City.
The opposition
Arsenal are unbeaten in their last 38 Premier League home games against promoted sides, winning each of the last nine including the dramatic turnaround against AFC Bournemouth last season.
This season, the Gunners have won all five of their league games against promoted sides, scoring 23 goals against them.
With eight goals and four assists, captain Martin Ødegaard has been involved in 12 goals in his last 12 Premier League appearances against promoted clubs.
Having provided just one assist in his first eight Premier League home games for Arsenal, Kai Havertz has now been involved in four goals in his last five at Emirates Stadium.
Words from Rob
"Every Premier League game is difficult, and they deserve the best preparation to try to put our best team out.
"I'm aware there's a game a few days later on Saturday but we are not really going to have anyone else that we don't have tomorrow, so it doesn't really make any difference.
"Arsenal’s defence is pretty stubborn, they don't give much away. It was a bit of a unique game, sometimes it can be at Kenilworth Road. Since the break around January time, Arsenal have come back and been incredible. I know they didn't score on the weekend, but they are scoring loads of goals and they are very, very difficult to break down.
"If we are able to go and score three at the Emirates then we're doing pretty well. We will try to be us and be the best version of us.
"It's difficult at the moment but, the reverse fixture was a really exciting game. We are going to be lower this time, we know that. They are so good with the ball they are going to force us low and defend really well. We can do a lot of work on that."
Last time out
Luton came minutes away from taking a crucial point away from the Tottenham Hotspur Stadium on Saturday.
Tahith Chong gave us the lead inside three minutes before an Issa Kaboré own goal and a late winner from Heung-min Son condemned us to defeat.
Team news
Reece Burke, Alfie Doughty and Tahith Chong were all forced off at Spurs and are "very doubtful" to feature on Wednesday, according to Edwards.
None of the other players who are currently injured will return for this game.
Last time we met
A seven-goal thriller went the way of the visitors when Arsenal came to Kenilworth Road in December.
Gabe Osho, Elijah Adebayo and Ross Barkley put the Hatters in the lead after Gabriel Martinelli and Gabriel Jesus netted in the first half.
The Gunners completed their comeback when Kai Havertz netted on the hour-mark and Declan Rice headed in the winner in the 97th minute.
Officials
The referee for our fixture against Arsenal will be Craig Pawson.
118 yellow cards and four red cards have been handed out by Pawson across his 25 games this season.
We last had a game officiated by Pawson when we beat Shrewsbury Town at Kenilworth Road back in February 2009 while in League Two.
Referee: Craig Pawson
Assistant Referees: Marc Perry & Steven Meredith
Fourth Official: Simon Hooper
VAR: Tim Robinson
AVAR: Daniel Robathan
LOVE FOOTBALL. PROTECT THE GAME.
Luton Town Football Club has committed in its customer charter to providing safe match-day experiences for all supporters regardless of age, gender, ethnicity, disability or sexual orientation, and this applies equally to home and away fixtures.
In the event that any Luton supporters do make discriminatory chants, the Club will work with the police and football authorities to help identify such individuals. Any such fans would then face the strictest club sanctions, including football banning orders that would prevent them attending any matches, in addition to any criminal charges.
The Club can also be held responsible for the behaviour of its supporters, which could lead to substantial fines being imposed.
As a diverse and inclusive football club, we stand shoulder-to-shoulder with our fellow Premier League clubs in supporting the FA’s ‘Love Football. Protect the Game’ campaign and call on all fans to enjoy the game in a positive spirit.
If you are offended by any discriminatory abuse of any kind at any of our games, you can report it by clicking here, or by contacting your nearest steward immediately. Alternatively, email myvoice@lutontown.co.uk or report the incident via Kick it Out's free, confidential reporting app on the App Store and Google Play.
Fan information
Arsenal have provided a guide on how to get to Emirates Stadium.
You can also find Arsenal's matchday safety and security information here.
