Cody Drameh returns to the starting line-up after missing the last two matches, replacing Fred Onyedinma who started in midweek.
Marvelous Nakamba makes his first home league start alongside Pelly-Ruddock Mpanzu and Jordan Clark in midfield, whilst Alfie Doughty is back on the bench after he missed out against Preston North End.
Luton Town: Horvath; Drameh, Burke, Lockyer (C), Osho, Bell; Nakamba, Mpanzu, Clark; Morris, Adebayo.
Substitutes: Shea, Potts, Berry, Woodrow, Campbell, Taylor, Doughty.
Burnley: Muric; Roberts, Ekdal, Taylor, Maatsen; Brownhill, Cullen, Cork (C); Tella, Gudmundsson; Barnes.
Substitutes: Peacock-Farrell, Twine, Foster, Zaroury, Vitinho, Al-Dakhil, Obafemi.
Referee: Jeremy Simpson