Following last weekend's 2-0 victory over rivals Watford, Edwards has entrusted the same starting XI and substitutes to take on Gary Rowett's side as they look to extend their unbeaten league run to nine matches.
Captain Tom Lockyer will lead the side out in South London along with Gabe Osho and Amari'i Bell in a back-three, supported by Cody Drameh and Alfie Doughty providing the width.
Aston Villa loanee Marvelous Nakamba - who completed a league record 10 tackles last weekend - accompanies Allan Campbell and Pelly-Ruddock Mpanzu in midfield, whilst top scorer Carlton Morris starts up-front with Elijah Adebayo.
For anyone not at The Den today, the match is live on Sky Sports Main Event - with build-up from 12pm. As usual, Simon Pitts is providing iFollow Hatters commentary and you can purchase an audio pass HERE.
Luton Town: Horvath; Drameh, Osho, Lockyer (C), Bell, Doughty; Nakamba, Mpanzu, Campbell; Morris, Adebayo.
Substitutes: Shea, Bradley, Berry, Woodrow, Lansbury, Burke, Taylor.
Millwall: Long; McNamara, Cooper, Hutchinson (C), Wallace; Saville, Leonard; Flemming; Voglsammer; Burke, Bradshaw.
Substitutes: Bialkowski, Malone, Mitchell, Shackleton, Watmore, Honeyman, Esse.
Referee: Darren England