Tom Ince and Elijah Adebayo made their respective first starts for the club after arriving on Deadline Day.
Joe Morrell and Ryan Tunnicliffe, who came on during Saturday’s match, are in from the start, as are Martin Cranie and Kal Naismith.
The Hatters are hoping to get back to winning ways under the lights at Kenilworth Road, in doing so ending a two-match losing streak.
Town: Sluga; Cranie, Bradley (C), Potts, Naismith; Tunnicliffe, Morrell, Dewsbury-Hall; Ince, Clark, Adebayo
Substitutes: Shea, Cornick, Berry, Hylton, Moncur, Rea, Mpanzu, Collins, Bree
Millwall: Bialkowski; Romeo, Hutchinson, Pearson, Malone; Thompson, Bodvarsson, Woods, Evans, Wallace, Bradshaw
Substitutes: Fielding, Tiensia, McNamara, Williams, Mitchell, Ferguson, Burey, Bennett, Smith.
Referee: Graham Scott