Allan Campbell comes into midfield alongside Pelly-Ruddock Mpanzu, whilst Harry Cornick partners Elijah Adebayo up-top, in place of Cameron Jerome who is amongst the substitutes.
Fred Onyedinma is back in the matchday squad after being forced off against West Brom, whilst there is a first home league start for Peter Kioso in defence.
Town: Sluga; Bree, Kioso, Lockyer, Naismith (C), Bell; Campbell, Mpanzu; Muskwe, Cornick; Adebayo.
Substitutes: Isted, Rea, Lee, Mendes Gomes, Onyedinma, Osho, Jerome.
Birmingham: Sarkic; Roberts, Dean (C), Pedersen; Colin, Sunjic, Woods, Bela; Chong, Hogan, Jutkiewicz.
Substitutes: Trueman, Friend, Leko, Aneke, Sanchez, Gardner, Castillo.
Referee: John Busby