Danny Hylton makes his first league start of the season up-front in place of James Collins, who misses out through injury.
After coming off the bench and scoring against Wycombe Wanderers, Elliot Lee starts as Jordan Clark is amongst the substitutes.
Newly capped Wales international Rhys Norrington-Davies makes his eighth consecutive start for the club and his fellow countryman and new signing Joe Morrell begins on the bench.
Yesterday's two new additions Sam Nombe and Kiernan Dewsbury-Hall aren't eligible for today's match but could be in contention to feature against Millwall on Tuesday evening.
Town: Sluga, Cranie, Pearson, Bradley (C), Norrington-Davies; Rea, Berry, Mpanzu; Cornick, Lee, Hylton.
Substitutes: Shea, Tunnicliffe, Moncur, Lockyer, Clark, LuaLua, Morrell.
Stoke: Davies, Batth, Souttar, Collins; Smith, Obi Mikel, Clucas (C), Powell, Tymon; Campbell, Fletcher.
Substitutes: Noukey, Ince, Vokes, Brown, Gregory, Oakley-Boothe, Thompson.
Referee: Jeremy Simpson