Kiernan Dewsbury-Hall makes his debut for the Town after joining on loan from Leicester City and starts alongside Joe Morrell, who makes his first start after coming off the bench in the last two matches.
Tom Lockyer is in for his first league start of the season and partners Matty Pearson and Sonny Bradley, the latter whom makes his 100th appearance for the club.
Elliot Lee is back in the starting line-up, whilst Sam Nombe could be called upon from the bench this afternoon.
Glen Rea and Harry Cornick are both absent due to injury, whilst Luke Berry, Jordan Clark and Kazenga LuaLua are among the substitutes.
Town: Sluga, Cranie, Pearson, Lockyer, Bradley (C), Norrington-Davies; Morrell, Mpanzu, Dewsbury-Hall, Lee, Hylton.
Substitutes: Shea, Tunnicliffe, Berry, Moncur, Clark, LuaLua, Nombe.
Sheffield Wednesday: Dawson, Odubajo, Flint, Van Aken; Harris, Bannan, Pelupessy, Reach; Paterson; Marriott, Kachunga.
Substitutes: Wildsmith, Palmer, Borner, Dele-Bashiru, Hunt, Windass, Rhodes.
Referee: Geoff Eltringham