The gaffer takes charge of his 200th Luton game in all competitions this afternoon and will hope to extend the current three-match unbeaten run at Kenilworth Road.
Matty Pearson returns to the starting eleven after serving his one match ban following his dismissal against Swansea City.
Kiernan Dewsbury-Hall starts also after coming on from the bench against Coventry in midweek, whilst George Moncur is the third change who begins in place of Jordan Clark, who is amongst the substitutes.
Town: Shea, Pearson, Lockyer, Bradley (C), Potts; Rea, Mpanzu, Dewsbury-Hall; Cornick, Moncur, Collins.
Substitutes: Isted, Cranie, Tunnicliffe, Berry, Clark, Norrington-Davies, LuaLua, Nombe, Morrell
Preston North End: Rudd, Fisher, Huntington, Davies, Hughes; Browne, Ledson; Barkhuizen, Potts, Sinclair; Stockley.
Substitutes: Ripley, Earl, Storey, Rafferty, Bayliss, Johnson, Gallagher, Maguire, Jakobsen.
Referee: Jeremy Simpson