Danny Hylton returns to the starting XI for the first time since away at Rochdale on November 3rd, with Harry Cornick - who went of injured before the break at Walsall on Saturday - dropping to the bench.
The Hatters will line up with James Shea in goal, Jack Stacey, Matty Pearson, Sonny Bradley and James Justin at the back, with Alan McCormack, Pelly-Ruddock Mpanzu, Andrew Shinnie and Elliot Lee in midfield.
Hylton and James Collins, who netted his tenth goal of the season in the 2-2 draw at the Banks's Stadium, are up front as the Town look to extend their unbeaten home start to the campaign, and their sequence without defeat to 14 matches in all competitions since losing at Barnsley in mid-October.
TOWN: Shea, Stacey, Pearson, Bradley (c), Justin, McCormack, Mpanzu, Shinnie, Lee, Hylton, Collins. Subs: Berry, Cornick, Grant, LuaLua, Jones, Sheehan, Isted.
BARNSLEY: Davies, Dougall, Pinnock, Lindsay, McGeehan, Cavare, Potts, Woodrow, Thiam, Mowatt, Williams. Subs: Hedges, Moncur, Jackson, Bahre, Adeboyejo, Brown, Greatorex.
REFEREE: John Brooks