The changed is an enforced one, with the suspended Amari'i Bell replaced by Dan Potts - who starts in the Sky Bet Championship for the first time since he was forced off through injury against Blackpool last month.
Carlton Morris scored the winner in the last meeting against the Canaries back in October and starts up front again with Elijah Adebayo.
There is a single change amongst the substitutes - with Cauley Woodrow fit and returning to the matchday squad ahead of midfielder Louie Watson.
Luton Town: Horvath; Bree, Osho, Lockyer, Potts (C), Doughty; Campbell, Mpanzu, Clark; Morris, Adebayo.
Substitutes: Isted, Cornick, Berry, Woodrow, Freeman, Jerome, Pettit.
Norwich City: Gunn; Aarons, Hanley (C), Omobamidele, Gibson, Giannoulis; Gibbs, McLean; Sara, Sargent; Pukki.
Substitutes: Krul, Byram, Hayden, Dowell, Idah, Hernandez, Nunez.
Referee: Tim Robinson