Town ran out 2-0 victors that day with goals from Andrew Shinnie and Harry Cornick booking a place in the second round, having already drawn 1-1 with the Buckinghamshire club at Adams Park in the first Sky Bet League One meeting of the season in September.
Tomorrow, still under the interim charge of Mick Harford, the Hatters are looking to extend their unbeaten run in the league to 19 matches - a sequence that would equal the club record for Football League matches without defeat.
That record was set twice in successive years half-a-century ago, first between January and April 1968, and then again from end of 1968/69 into the 1969/70 campaign.
Town go into the game six points clear at the top of the division, and unbeaten at Kenilworth Road this season in the league.
Leading scorer James Collins has been named the division's player of the month for January - when he scored six times in five matches - although Harford missed out on the managerial award to Scunthorpe's Stuart McCall.
It is set to be a landmark occasion for home-grown defender James Justin, who is in line to make his 100th senior appearance for the club.
Wycombe, who are managed by Gareth Ainsworth, who played under Harford when he was a coach at both Wimbledon and QPR, are in good form themselves, arriving at the Kenny on the back of a five-match unbeaten run that has lifted them to within six points of the play-offs.
MICK HARFORD SAYS:
On coming up against Gareth Ainsworth: "I know Gareth very well. I've know him for a long, long time. I was coaching at Wimbledon with Joe Kinnear when we signed Gareth from Port Vale, and he's a great lad. He has a great attitude and his team will mirror him because of the work ethic and the way he wants to play. They've been very difficult opponents whenever we've played them, and on numerous times this season I've watched them, and they are real well-oiled outfit who know what they're doing. They'll have a shape which they play to and it's going to be a tough test for us."
On assistant manager Steve Rutter: "Steve came in and he's a very technical coach, he's a great ally for any manager, he does a great job and has a good rapport with the players. He sees things differently to a lot of us, so he's been a great asset to the football club and he's been great for me while I've been in this role, so I thank him for his efforts along with Inigo and the rest of the staff."
On his nomination for Manager of the Month: "I keep saying it, but I was absolutely thrilled to be offered the role as interim manager and it's a privilege to do it - especially being in charge of these bunch of lads because they are a credit. It's testament to what the staff, the players and what we've done in the last month. It was a privilege and I'm delighted to have been nominated."
On James Collins winning Player of the Month: "James has been on fire. He’s deservedly, in my opinion, won the award – not just on goals scored but on his work-rate and his effort. He’ll be the first to commend his team-mates for the assists that they’ve laid on for him, but he’s worked hard and I’m really pleased for him. His work-rate is phenomenal. He gets around the pitch, he closes people down. We put him in a position where he’s very good at defending corners, in that little hole that we put him, and overall he’s been a massive, massive bonus for us in terms of his goals and his whole contribution."
On James Justin making his 100th senior appearance: "We believe James is going to be something special as a player and I didn't realise it was his 100th game coming up. That's some achievement for such a young lad. He got into the team, he's cememted his place. He's holding his place down at lefy-back, despite being predominantly a right-back and he can fill in various roles, so he'll be thrilled, his family will be delighted because they are all Luton Town fans, and I'm proud of him. He's a great kid and I'm so happy for him."
YOU CAN WATCH MICK'S PRE-MATCH PRESS CONFERENCE ON IFOLLOW FREEVIEW BY CLICKING HERE.
WHO?
Formed in 1887, the Chairboys have played a large part of their history in Non-League football. They won promotion under Martin O’Neill to the Football League in 1993, winning successive promotions as they went up to the Second Division. They have remained in the EFL since and have bounced between the third and fourth tier in that time, winning promotion back up to League One alongside the Hatters and Accrington last season.
WHEN AND WHERE?
Kick-off is at 3pm at Kenilworth Road on Saturday 9th February.
MAN IN THE MIDDLE?
Tomorrow's match will be refereed by Andy Davies, a Select Group 2/Championship official who last refereed us away at AFC Wimbledon in October. He has shown 84 yellows and six red cards in his 25 games this season.
TICKET INFORMATION
Due to season ticket holders who are unable to make tomorrow’s game releasing their seats, we now have a few seats available. We also have a number of single and restricted view seats available. Please contact the Ticket Office on 01582 416976 or book online ASAP!
POWER COURT CAR PARKING
Take advantage of the fantastic car parking deal we have on for supporters, click here for more info!
AWAY SUPPORTERS
If you're a Wycombe supporter heading to Kenilworth Road for tomorrow's game, click here to have a look at our away supporters' guide.
PLAYED BEFORE?
We’ve already played Wycombe twice this season, with Matty Pearson netting the equaliser in the league game at Adams Park on 1st September after Joe Jacobson - who would later see a second-half penalty saved by James Shea - had given the Chairboys the lead. The two sides then met in the first round of the Emirates FA Cup at the Kenny, with the Hatters progressing with a 2-0 win. Of our 27 meetings with Wycombe, Town have won 12, drawn 10 and lost five.
FOLLOW THE ACTION
The main blow-by-blow account of the action from Kenilworth Road will be provided via the Match Centre on the club website, which you can access by clicking here. (*Please note that the club's Live Text will appear only by accessing through an internet browser, users of the Luton Town FC app will receive updates from Opta)
The main moments from the game will appear on the Hatters' social media feeds:
Twitter – @LutonTown
Facebook – www.facebook.com/LutonTown/
Instagram – www.instagram.com/ltfc_official/
And of course Simon Pitts will be on hand to provide commentary for iFollow Hatters which you can subscribe to by clicking here.
If you're an international subscriber, make sure you purchase a match pass so you can watch the game live!