Rob Edwards’ side are aiming to get back to winning ways with the Hatters four points behind Nottingham Forest in 17th place.
Oliver Glasner’s Palace have seen an improvement in performance since the Austrian’s appointment last month.
The opposition
Glasner arrived in South London after Roy Hodgson stepped down from his post at Selhurst Park less than three weeks ago.
It was a successful start for Glasner as the Eagles scored three in the second half against ten-man Burnley in his opening game.
Palace have won four of their five Premier League games against promoted sides this season, the only exception being the defeat at Kenilworth Road in the reverse fixture.
Eberechi Eze has scored four goals in his last four Premier League games, while he has eight in his last 10 appearances at Selhurst Park stretching back to last April.
This will be Palace’s first league game against Town at Selhurst Park since a Championship match in February 2007.
Team news
Gabe Osho will be left until the last minute before Rob Edwards decides whether to select the defender, who is recovering from a muscular issue.
Last week's scorer Tahith Chong will be fit for selection after being substituted in the game against Aston Villa.
All other players who have been unavailable remain out.
Last time out
Luton were minutes away from a memorable comeback against Villa at Kenilworth Road before the visitors found a late winner.
Ollie Watkins’ double left the Hatters two-down at half-time; Tahith Chong and Carlton Morris brought us level after the break before Lucas Digne’s 89th minute header sealed the win for Villa.
Last time we met
Luton secured our first-ever Premier League home win when we beat Palace at Kenilworth Road in November.
Teden Mengi scored his first senior goal before Michael Olise hit a screamer moments later. Jacob Brown was the hero when he came off the bench to score the winner.
Officials
The referee for our fixture against Palace will be Sunny Gill.
137 yellow cards and six red cards have been handed out by Gill across his 37 games this season.
This will be Gill’s first match officiating in the top-flight and he will be the first British South Asian to referee a Premier League fixture.
Referee: Sunny Singh Gill
Assistant Referees: Edward Smart & Nick Greenhalgh
Fourth Official: Tim Robinson
VAR: Peter Bankes
AVAR: Matthew Wilkes
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