Hoping to extend their three-game unbeaten run in the league, a win could take the Hatters into the play-off places, if results also go their way.
The opposition:
Barnsley find themselves bottom of the Sky Bet Championship after a barren run of form. Without a league win since November 3rd, the Tykes are in need of inspiration from Carlton Morris, their joint-top scorer, who has recently returned to the team after a period of absence.
Last time we met:
Amari'i Bell scored his first Luton goal in a 1-0 away win back in August. The left-back scored early on in the game and the Hatters held out to register their first away win of the season.
Follow the action:
UK-based fans will be able to watch the match on iFollow as this is a midweek home fixture.
Overseas supporters can watch all live EFL Championship league matches provided that they have not been selected for international television broadcast in a territory that has an overseas broadcast provider.
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Ref watch
Referee: Andy Davies
Assistant Referees: Graham Kane and Robert Hyde
Fourth Official: Trevor Kettle
The man in the middle on Tuesday night is Andy Davies, who last took charge of the Hatters' 0-0 draw against Sheffield United in August 2021.
He has officiated 23 matches in total, dishing out 64 yellow cards and two reds in the process.