Hatters boss Nikki Baker says her side are looking forward to the game, as they look to make club history.
She said: "We are very proud to have reached a national final for the first time and the girls are relishing the opportunity to play against another team in the league above. So far we have represented ourselves brilliantly against teams from the level above, taking Chichester all the way to the end in the FA Cup, followed by a very narrow and late defeat against Fylde.
"It has been a frustrating few weeks for us with a lot of change in the dugout as well as on the pitch, with me starting maternity leave and having a small player turnover. The girls have pulled together really well as a group and overcome a couple of difficult results.
"We have had a good season in all three cups, reaching the final of the FAWPL Plate, as well as the Bedfordshire County Cup Final where we will look to retain our title. In the FA Cup we had a good run and were knocked out by Chichester who eventually went a long way in the competition, showing how well we performed in that game."
The Town will take on West Ham United at the home of Hednesford Town, with the game kicking off at 3pm.
The Hammers sit in the division above the Hatters, but Baker expects to see her side put in a strong performance.
"Myself, the rest of the management team and the players are looking forward to the opportunity to play West Ham and give a good account of ourselves," she continued.
"We know they are a good side and have the financial backing of the club which enables them to aim for the top. However, we believe in ourselves and know that on our day, we can compete with any club in the FAWPL, having proved this on several occasions.
"If we play with confidence and stick to our game plan, we know we can take the game to West Ham and we can't wait for chance to show this."
Good luck ladies!